GuidelineACR Incidental FindingsCT / MRIAdrenal Algorithm

Adrenal Incidentaloma

ACR Incidental Findings · Updated 2023 revision

Size, washout thresholds, and follow-up cadence for the incidental adrenal mass.

Bottom line

≤4 cm + benign features: no follow-up. Indeterminate: dedicated adrenal CT.

Applies to

Incidentally detected adrenal nodules on CT or MRI in adults

Does NOT apply to

Patients with known primary malignancy staged with dedicated adrenal protocol · Suspected pheochromocytoma with biochemical work-up already positive

Modality

CT / MRI

Evidence

ACR Incidental Findings White Paper

30-second summary

≤ 4 cm with benign features → no follow-up. Indeterminate → dedicated adrenal protocol CT with washout or chemical-shift MRI.

Overview

Size, washout thresholds, and follow-up cadence for the incidental adrenal mass.

Quick reference

Size / density — management
FindingManagement
≤ 4 cm, benign HU (< 10) or macro fatNo follow-up
≤ 4 cm, indeterminateAdrenal CT washout or CS-MRI
> 4 cm, no prior imagingEndocrine work-up ± resection
Growth ≥ 5 mm/yearConsider resection

Decision algorithm

Interactive
Adrenal Incidentaloma Algorithm

Work-up of the incidental adrenal mass discovered on abdominal CT.

Walk through algorithm

References

  • Mayo-Smith WW et al. JACR 2017 — ACR Incidental Adrenal
    Open